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Related Information. Close Figure Viewer. Browse All Figures Return to Figure. Previous Figure Next Figure. Email or Customer ID. Forgot password? Old Password. At the level of the citric acid cycle , arsenic inhibits lipoic acid , which is a cofactor for pyruvate dehydrogenase. Hydrogen peroxide production is also increased, which, it is speculated, has potential to form reactive oxygen species and oxidative stress.
These metabolic interferences lead to death from multi-system organ failure. The organ failure is presumed to be from necrotic cell death, not apoptosis , since energy reserves have been too depleted for apoptosis to occur. Although arsenic causes toxicity it can also play a protective role. Occupational exposure and arsenic poisoning may occur in persons working in industries involving the use of inorganic arsenic and its compounds, such as wood preservation, glass production, nonferrous metal alloys, and electronic semiconductor manufacturing. Inorganic arsenic is also found in coke oven emissions associated with the smelter industry.
Treatment of chronic arsenic poisoning is possible. From Wikipedia, the free encyclopedia. This article is about the chemical element. For the poison commonly called arsenic, see arsenic trioxide. For other uses, see Arsenic disambiguation. Chemical element with atomic number Main article: Isotopes of arsenic. See also: Category:Arsenic compounds. Main article: Organoarsenic chemistry.
See also: Arsenide minerals and Arsenate minerals. Main article: Arsenic biochemistry.
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